The CHRNA9 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to CHRNA9. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The CHRNA9 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane(PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane(PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion(PubMed:11021840)